DESCRIPTION

The concept of microfabricated structures for total chemical analysis embodies a vision wherein the total analysis of complex samples is carried out in a completely integrated "chip." Landers et al. have previously proposed the development of an Integrated Diagnostic Chip (ID Chip), wherein sample preparation, DNA amplification, and electrophoretic analysis will be carried out directly on the chip for detection of various forms of cancer. The present invention is a method for the precise manipulation of nanoliter/picoliter volumes in microfluidic chips by enhancing electroosmotic flow in the ID Chip. This method allows for the controlled movement of fluids within microfluidic devices. This method requires application of only an external voltage to provide spacial, temporal, and volumetric control of fluid movement.

STATUS: Available for licensing and collaboration

CONTACT

Alan Bentley
University of Virginia
Patent Foundation
1224 West Main Street
Suite 1-110
Charlottesville, VA 22903

Phone: 804-982-1615
E-mail: abentley@virginia.edu

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